From Wikipedia: (Uncanny X-Men)
Uncanny X-Men, first published as The X-Men, is the flagship Marvel Comics comic book series for the X-Men franchise, featuring the adventures of the eponymous group of mutant superheroes. While hugely successful now, the book was initially met with a lukewarm reception, and took a number of years for the X-Men’s first issue (cover dated September 1963) to secure even mild success. The series was cancelled in 1970, but interest was rekindled with 1975’s Giant-Size X-Men and the debut of a new, international team. Under the guidance of writer Chris Claremont (whose 16-year stint began with August 1975’s Uncanny X-Men #94), the series grew in popularity worldwide, eventually spawning a franchise with numerous spin-off “X-books,” including New Mutants, X-Factor, Excalibur, X-Force, Generation X, the simply titled X-Men, and a number of prefixed titles such as Astonishing X-Men and New X-Men.
It was announced by Marvel that the series will conclude after the “Schism” storyline with #544 (February 2012). 
I used to read the Uncanny X-Men. I started at around #160 or so and ended somewhere around #245, I think. It was a good run, and I enjoyed the stories. They were better in the early years, though. Everything after Secret War II was not very well written, in my estimation.
Regardless, this is our Open Thread. Feel free to discuss the X-Men or whatever else strikes your fancy.